Abstract: By use of the statistics obtained from the experimental wall panels under failure mode, an SVM model is thus established for predicting failure load through failure mode under lateral Uniformly-Distributed loads. In combination with the principle of the gray co-occurrence matrix, the coincidence relation is established between the failure observation records of wall panels of different sizes and fixed-dimension general failure modes of wall panels. Using the normalized failure load as the output data of the training and testing samples, it proves to be valid and feasible through numerical examples, which finds a novel approach for the study of the failure load of the masonry wall panel.