Abstract: New textbook is a necessity and the major content for the implementation of new curricular reform. By aid of bibliographical reference, an exploration was made into the innovation points in the content design of high school Experimental Chemistry published by Jiangsu Educational Press. The findings show that the innovation points lie chiefly in the following aspects: careful selection and design of the experimental content; an increase of explorativeness, real-life orientation and fun in aspects like the structural design and question design. The book boasts its rich design formats, interesting content and the well-arranged hierarchies. By application of methods like induction, analogy and thinking migration, it makes a lot easier to handle and master the experimental approaches and the use of the experiments listed in the book in classroom teaching can enlighten innovatory thinking and help develop students’ experimental skills and their scientific literacy.