Abstract: Content of moisture, ashes and extracts of Ophiopogon Japonicus, a geo-authentic crude drug produced in Santai county of Sichuan province, were determined by methods proposed in Chinese pharmacopoeia(2010 edition). The results showed that moisture content in Ophiopogon japonicus was between (9.77±0.27)%～(12.41±0.41)%, with an average content of about 10.69%. The ashes content in Ophiopogon japonicus was between (2.43±0.06)%～(3.05±0.08)% , and the average content of ashes was 2.84%. Extracts content in Ophiopogon japonicus lies between (70.91±0.97)%～(76.12±1.30)%, and the content of extracts averages 73.80%. All of them satisfy the standards prescribed in Chinese pharmacopoeia (2010). Meanwhile the moisture was less than 14.0%, the total ashes content was well under 4.0 %, the content of extracts was no less than 70%, which provided experimental data for the establishment of quality standards of Ophiopogon japonicus and can serve as a basis for the local use of Ophiopogon japonicusin Sichuan.