Abstract: Taking students majoring in the flight technology as the research samples, several statistical methods were used in the analysis of the factors affecting student’s mathematics academic performance so as to investigate the impact of the factors like the teacher’s teaching ability, the students’ mathematics score of the college entrance examination that may have upon their academic performance at college. The results showed that the teaching level of a teacher and the student’s mathematics score of the college entrance examination had significant effects on his/her mathematics achievement at college. However, the mathematics results in college entrance examination can only explain 12.6 per cent of total variation of their college mathematics academic performance. It can be safely concluded that the teaching level of a teacher and the student’s learning autonomy could greatly promote students’ mathematics achievement.