Abstract: After constructing the comprehensive development indices for industrial structure change and new urbanization, the concept of new urbanization response intensity index of industrial structure change was introduced with 16 prefecturelevel cities in the Chengdu-Chongqing Economic Zone taken as the research subjects so as to explore the inner relation between industrial structure change and new urbanization from two dimensions:industrial structure rationalization and height.On this basis, the regional types of the new urbanization response in 16 cities are divided into three types:uniform response, partial Rtl positive response and partial Rtspositive response.According to the development status of the new urbanization response intensity of the industrial structure changes in the 16 cities of the Chengdu-Chongqing Economic Zone, the corresponding countermeasures for the coordinated development of different regions were put forth.