刘荟琦, 唐 可, 熊 玲, 张仲明. 强迫症反应抑制研究范式综述[J]. 内江师范学院学报, 2016, (10): 100-105. DOI: 10.13603/j.cnki.51-1621/z.2016.10.019
    引用本文: 刘荟琦, 唐 可, 熊 玲, 张仲明. 强迫症反应抑制研究范式综述[J]. 内江师范学院学报, 2016, (10): 100-105. DOI: 10.13603/j.cnki.51-1621/z.2016.10.019
    LIU Hui-qi, TANG Ke, XIONG ling, ZHANG Zhong-ming. Review of Research Paradigms for Response Inhibition in Obsessive Compulsive Disorder[J]. Journal of Neijiang Normal University, 2016, (10): 100-105. DOI: 10.13603/j.cnki.51-1621/z.2016.10.019
    Citation: LIU Hui-qi, TANG Ke, XIONG ling, ZHANG Zhong-ming. Review of Research Paradigms for Response Inhibition in Obsessive Compulsive Disorder[J]. Journal of Neijiang Normal University, 2016, (10): 100-105. DOI: 10.13603/j.cnki.51-1621/z.2016.10.019

    强迫症反应抑制研究范式综述

    Review of Research Paradigms for Response Inhibition in Obsessive Compulsive Disorder

    • 摘要: 强迫症反应抑制的研究常用的四种范式(Go-Nogo范式、Stroop范式、停止信号范式、负启动任务)各有其优缺点. Go-Nogo范式的实验任务相对简单,得出的结果在一定程度上能解释反应抑制,但是Go-Nogo范式中使用的实验材料过于简单,且多为与强迫症无关,生态效度较低; 相对于Go-Nogo范式,Stroop范式在实验材料上除了色词之外,还运用了一些强迫症有关的情绪词,提高了实验的生态效度,因此,现关于强迫症反应抑制的研究多数研究者选择使用Stroop范式; 停止信号范式在某种程度上与Go-Nogo范式相似,也在其基础上有所发展,它不但具备了Go-Nogo范式的优点,同时参考的指标也更为丰富; 与其他几种研究范式相比负启动任务在反应抑制的研究中运用较少,其优点是可以设置不同的时间间隔,提高实验的灵活性.最后通过对前人的研究的分析总结,对强迫症抑制缺陷未来研究的方向和趋势进行了展望.

       

      Abstract: Each of the most commonly used four research paradigms for OCD response inhibition(Go-Nogo, Stroop, Stop Signal and Negative Priming Task)has its pros and cons. The Go-Nogo paradigm has relatively simpler tasks and the conclusions it produces can in some degree explain the response inhibition, yet the experimental materials used are much too simple and most of them are irrelevant to OCD, so the ecological validity is rather low; compared with the Go-Nogo paradigm, the Stroop paradigm uses richer experimental materials like words of emotion, besides the use of words of color, thus the ecological validity is enhanced. That's why most of the current OCD response inhibition researches adopt the Stroop paradigm; the Stop Signal paradigm, to some degree, is similar to the Go-Nogo paradigm, yet it still has made some improvements on it, so it not only possesses the advantages of Go-Nogo paradigm, but also has a richer indices of reference; the Negative Priming Task paradigm is the least commonly used research paradigm of the four, whose advantage lies in that it can set different time intervals thus to enhance the flexibility of the experiments. Through the analysis and summary of the previous researches, an outlook of the future research orientations and trend is done concerning the OCD inhibition deficiency.

       

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